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Comparison the effect of IV Ibuprofen and IV Ketorolac on post operation pain.

The comparison of efficacy and side effects of IV( intravenous) Ibuprofen and intravenous Ketorolac in laparoscopic cholecystectomy patients.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171003036530N2
Enrollment
90
Registered
2018-09-03
Start date
2018-05-05
Completion date
Unknown
Last updated
2018-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cholecystitis. cholecystitis

Interventions

Intervention 1: The first Intervention group will receive a pain pump containing Fentanyl 100 ml and then intravenous Ketorolac 30 mg at intervals of zero, 8 and 16 hours after surgery. Intervention 2

Sponsors

Ardabil University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients who are undergoing laparoscopic cholecystectomy surgery at Imam Khomeini Hospital in Ardebil. Being at the age of 20 and 60 years old Patients who accept to participate in the research.

Exclusion criteria

Exclusion criteria: Pregnancy History of Asthma and Pulmunary disease History of heart disease History of CKD (chronic kidney disease) or dialysis History of GI (Gastrointestinal) bleeding History of HTN (hypertension) History of Anemia Using Warfarin Consumers simultaneously ACEI (angiotensin converting enzyme inhibitor) and Furosemide Drug dependence Allergic reaction to ibuprofen or NSAIDS or celecoxib

Design outcomes

Primary

MeasureTime frame
Abdominal pain. Timepoint: 6,12 ,18, 24 hours after the operation, pain will be evaluated. Method of measurement: The assessment of abdominal pain is based on the Visual Analogue Scale system.;Shoulder pain. Timepoint: 6,12,18,24 hours after surgery. Method of measurement: The assessment of pain is based on the Visual Analogue Scale system.;Nausea and Vomiting. Timepoint: 6,12,18,24 hours after surgery. Method of measurement: The assessment is based on the N/V(Nausea and Vomiting)system.;Loss of consciousness. Timepoint: 6,12,18,24 hours after surgery. Method of measurement: The assessment is based on the Ramsay score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomaye Hoghughi

Ardabil University of Medical Sciences

sagarmehrmed@yahoo.com+98 45333582779

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026