Acute Myocardial Infarction. Acute myocardial infarction
Conditions
Interventions
Treatment - Drugs
All patients will receive Emergency PCI treatment. Patients will receive 300 mg of chewing aspirin and 600 mg of Clopidogrel maintenance dose prior to the procedure before transferring to the catheter
Sponsors
Deputy of Research of Guilan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Ischemic typical chest pain extending more than 30 min; ST elevation more than 1 mm in at least 2 leads with the same name; all patients with STEMI candidate for primary PCI; myocardial infarction not extending more than 12 hours; having life expectancy not less than 6 months; consent for participation in the study; age 18 to 80 years; no evidence for prior myocardial infarction; not having contraindications for reteplase or eptifibatide; not having left bundle branch block; not using GPIIb/IIIa in recent two weeks.
Exclusion criteria
Exclusion criteria: Exclusion criteria: Rescue PCI after thrombolytic therapy; emergency CABG; AF; cardiogenic shock; TIMI flow grade 3 in primary angiography
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coronary blood flow. Timepoint: before and after primary PCI. Method of measurement: based on angiographic scale TIMI blush grade. | — |
Secondary
| Measure | Time frame |
|---|---|
| Left ventricular diastolic dysfunction change. Timepoint: before and after angiography. Method of measurement: according to echocardiographic criteria.;ST resolution average. Timepoint: before and 90 minutes after PCI. Method of measurement: based on electrocardiogram.;Average of EF changes. Timepoint: before and 3 to 4 days after angioplasty. Method of measurement: based on echocardiography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMostafa Zadkamali
Guilan University of medical sciences
Outcome results
None listed