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The effect of nicotine patch on reducing nausea and vomiting and postoperative pain

The effect of nicotine patch on reduction of nausea and vomiting and pain following bile duct surgery using laparoscopic method

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017092336328N1
Enrollment
100
Registered
2017-10-04
Start date
2017-08-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: nausea and vomiting. Condition 2: Postoperative pain. Vomiting following gastrointestinal surgery Pain, unspecified

Interventions

Intervention 1: In the intervention group labels containing 17.5 mg nicotine for 24 hours, were made in England. Intervention 2: In the control group, the drug-free labels of Osveh Company were used.
Treatment - Drugs
Placebo
In the intervention group labels containing 17.5 mg nicotine for 24 hours, were made in England
In the control group, the drug-free labels of Osveh Company were used.

Sponsors

Ardabil University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: aged 18 to 65 years of age ; Non-smoking patients ; Not having a history of heart disease and nervous disorders, diabetes and hypertension Exclusion criteria: Patients with scores of pain above 8 on the basis of pain assessment criteria ; Receiving an additional pain reliever for pain control ; Patients requiring laparotomy ; Patients unable to maintain a nicotine pach for 24 hour

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 1st, 6th, 12th and 24th hours after surgery. Method of measurement: Visual Scale of Pain.;Nausea and vomiting. Timepoint: 1st, 6th, 12th and 24th hours after surgery. Method of measurement: Nausea and vomiting evaluation checklist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMir salim Seyed sadeghi

Ardabil University of Medical Sciences

fatemi@arums.ac.ir s.seyedsadegi@arums.ac.ir+98 45 3323 2520

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026