deformations and chromosomal abnormalities. Female infertility associated with anovulation
Conditions
Interventions
Intervention 1: Intervention group: In the intervention group, simultaneously with ICSI, an appropriate percentage of the cytoplasm of the young egg (fresh or frozen and thawed) is transferred to the
Sponsors
Iranian academic center for education culture and research
Eligibility
Sex/Gender
Female
Age
40 Years to 45 Years
Inclusion criteria
Inclusion criteria: Age over 40 years FSH higher base12.5 IU/l One or more failed IVF/ICSI or less than 5 retrieved eggs or high FSH use for stimulation >3000 international units or low ovarian response to stimulation
Exclusion criteria
Exclusion criteria: Age less than 40 years Male-related infertility First cycle of treatment Pelvic organ injuries, congenital adrenal hyperplasia, thyroid dysfunction, Cushing's syndrome, severe liver or kidney disease, or active peptic ulcer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Studying the effect of egg cytoplasm transfer on fertilization rate. Timepoint: 24 hours after sperm injection into the egg cytoplasm. Method of measurement: Inverted microscope. | — |
Secondary
| Measure | Time frame |
|---|---|
| Studying the effect of egg cytoplasm transfer on the number and quality of embryos. Timepoint: 72 hours after sperm injection into the egg cytoplasm. Method of measurement: Inverted microscope. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactatefeh verdi
Iranian academic center for education culture and research
Outcome results
None listed