Skip to content

Correction of Complications of Endometriosis by Curcumin Nanomicelle Supplement in Treated Women

Supplementary Curcumin Nanomicelle Drug for Effective Treatment of Infertile Endometriosis Patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170923036334N4
Enrollment
20
Registered
2022-05-09
Start date
2022-04-21
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis. Endometriosis of Ovary

Interventions

Intervention 1: Intervention group: In the intervention group, 10 patients with endometriosis are treated orally for 10 weeks with a daily dose of 120 mg of nanocell curcumin supplement (40 mg). Nano

Sponsors

Iranian academic center for education culture and research
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Age between 20-40 Years Endometriosis With Grade 2 and 3

Exclusion criteria

Exclusion criteria: No ovulation Male factor infertility Pelvic organ prolapse Congenital adrenal hyperplasia Thyroid hormone disorders

Design outcomes

Primary

MeasureTime frame
Evaluation of serum levels of sex hormone. Timepoint: Before taking the drug and 10 weeks after taking the drug. Method of measurement: Eliza Kit.;Evaluation of biochemical factors. Timepoint: Before taking the drug and 10 weeks after taking the drug. Method of measurement: Abnova commercial kits using ELISA method.;Measurement of Plasma Curcumin Levels. Timepoint: Before Taking the Drug and 10 Weeks After Taking the Drug. Method of measurement: Negative Electrospray Ionization (ESI) and Data are Analyzed Using MassLynx v4.0 Software.;Apoptosis Levels. Timepoint: Before Taking the Drug and 10 weeks After Taking the Drug. Method of measurement: Tunnel Kit.

Secondary

MeasureTime frame
Fertility Rate. Timepoint: One Day After Injection of Sperm into the Cytoplasm of the Oocyte. Method of measurement: Fertilization is Seen with an Inverted Microscope.;Embryo Quality. Timepoint: Three Days After Sperm is Injected into the Cytoplasm of the Oocyte. Method of measurement: Embryo Quality is Assessed Based on the Number of Cells and the Number of Blastomeres and the Fragmentation of the Blastomeres and is Observed Under an Inverted Microscope.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtefeh Verdi

Iranian academic center for education culture and research

Atefeh.Verdi@Yahoo.Com+98 25 3270 0155

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026