oligospermia. ????????? ????? ?????? XIV
Conditions
Interventions
Intervention 1: 1-Control group:In the control group, at least 25 ICSI patients were not treated with rhFSH and sperm analysis was performed based on WHO-2010 criteria and DNA damage and blood serum w
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
Male
Age
25 Years to 45 Years
Inclusion criteria
Inclusion criteria: Oligozospermia infertile men
Exclusion criteria
Exclusion criteria: Men with varicocele, history of varicoceles surgery, systemic disease or taking medication for systemic disease, chemotherapy or radiotherapy history, anatomical problems in the genitals, including testicular atrophy, treatment with antidepressants, are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sperm parameters. Timepoint: In this study, the evaluation of sperm parameters before and after rhFSH is evaluated and the rate of use of rhFSH is three months. Method of measurement: Clinical analysis of semen standard for sperm parameters with the usual laboratory method and optical microscope according to WHO-2010 WHO criteria.;DNA Damage. Timepoint: In this study, the evaluation of DNA damage before and after taking rhFSH is measured and the rate of use of rhFSH is three months. Method of measurement: DNA damage is done using the SDF laboratory kit and optical microscope.;The amount of hormone FSH. Timepoint: In this study, the amount of FSH is measured before and after the administration of the drug, and the rate of use of rhFSH is three months. Method of measurement: Measurement of FSH levels is done by ELIZA commercial kits. | — |
Secondary
| Measure | Time frame |
|---|---|
| Check fertilization rates. Timepoint: One day after sperm injection into the oocyte cytoplasme . Method of measurement: Fertilization can be seen with an inverted microscope.;Quality of the embryo. Timepoint: Three days after sperm injection into oocyte cytoplasm. Method of measurement: Evaluating the quality of the embryo is based on the number of cells and the number of blastomers and the fragmentation of the blastomers and is observed with the Invert microscope.;Pregnancy. Timepoint: 14 days after the transfer of the embryo into the uterus. Method of measurement: Pregnancy testing is done by giving beta-HCG. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAtefeh Verdi
Islamic Azad University
Outcome results
None listed