Idiopathic chronic urticaria. Other urticaria
Conditions
Interventions
every 10 days, 1 tablet of 50,000 units of vitamin D is given to the patient..
Treatment - Drugs
every 10 days, 1 tablet of 50,000 units of vitamin D is given to the patient.
Sponsors
Vice chancellor for research, Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: Chronic urticaria affected for more than 6 weeks, negative skin Prick test for common respiratory allergens. Patient's willingness to take medication and participate, The serum level of 25 OH vit D Should be less than 10 ng / ml Exclusion criteria: taking Corticosteroid drug during the past week. having Other allergic diseases and Infectious diseases and Autoimmune disease Normal levels of vitamin D
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: Befor the trial. Method of measurement: DLQI Questionnaire.;Utricaria severity. Timepoint: Befor the trial. Method of measurement: USS Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| IL-17 Exprssion. Timepoint: After the trial. Method of measurement: Real-time PCR.;IL-10 Exprssion. Timepoint: After the trial. Method of measurement: Real-time PCR.;TGF-B Expression. Timepoint: After the trial. Method of measurement: Real-time PCR.;Foxp3 expression. Timepoint: After the trial. Method of measurement: Real-time PCR. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShima Zarei
Mashhad University of Medical Sciences
Outcome results
None listed