Lymphedema.
Conditions
Interventions
Treatment - Drugs
Sponsors
Vice chancellor for research, Iran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Women with unilateral Breast Cancer Related Lymphedema; breast cancer lymphedema in STAGE = 2; age range of 18-60 years; BMI between 25 and 35; At least one month has passed since the last treatment such as radiotherapy; willingness to participate in the study Non-inclusion criteria: use of multi-vitamin minerals and omega-3 supplements up to 1 month before the study began; acute and chronic infection; history of autoimmune diseases such as rheumatoid arthritis; Inflammatory diseases such as heart failure, pulmonary, kidney and diabetes; taking supplements of probiotics from 6 months before study; having a weight loss diet in Length 6 months before the study; Smoking and alcohol consumption; Lymphedema due to other cancers Exclusion criteria : Unwillingness of the patient to continue research collaboration; No subsequent referral; Cancer recurrence during the study; Failure to follow a weight loss diet; Consumption of food and supplements containing probiotics during the study; Incidence of edema-like diseases such as renal, cardiovascular and respiratory failure during the study period; Metastasis; Infectious diseases in Study length; Consumption of less than 56 capsules of 70 capsules at the end of the study
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IL-10. Timepoint: Before and after the intervention. Method of measurement: ELISA. | — |
Secondary
| Measure | Time frame |
|---|---|
| TGF-ß. Timepoint: Before and after the intervention. Method of measurement: ELISA.;VEGF. Timepoint: Before and after the intervention. Method of measurement: ELISA.;Adiponectin. Timepoint: Before and after the intervention. Method of measurement: ELISA.;BMI. Timepoint: Before and after the intervention. Method of measurement: Weight ratio (kg) to squared height (m).;Skin fold thickness. Timepoint: Before and after the intervention. Method of measurement: caliper.;Waist. Timepoint: Before and after the intervention. Method of measurement: Meter (cm).;Waist to hip ratio. Timepoint: Before and after the intervention. Method of measurement: Calculate.;Nutrition status. Timepoint: Before and after the intervention. Method of measurement: Measurement of energy and nutrients intake using a 24-hour dietary recall questionnaire and anthropometric indices using scales and measurements.;Volume of lymphedema. Timepoint: Before and after the intervention. Method of measurement: water tank technique.;Physical activity. Timepoint: Before and after the intervention. Method of measurement: IPAQ questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMitra Zarrati
Iran University of Medical Sciences, School of Public Health
Outcome results
None listed