Comparison of intravenous Dexmedetomidine and Clonidine in change of ?hemodynamic parameter and block quality after spinal anesthesia with ?Ropivacaine in lower limb orthopedic surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017092020258N60

Enrollment

120

Registered

2017-10-28

Start date

2017-04-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal. Other complications of anaesthesia

Interventions

Intervention 1: intervention group 2: We will inject Clonidine 0/2 micro gram in kilogram in hours. Intervention 2: Control group: We will inject 50 millimeter in litter normal salin. Intervention 3:

Treatment - Drugs

intervention group 2: We will inject Clonidine 0/2 micro gram in kilogram in hours.

Control group: We will inject 50 millimeter in litter normal salin.

intervention group 1: We will inject Dexmedetomidine 0/1 micro gram in kilogram in hours

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 18 to 60 years; ASA class I and II; both male and female; patients with lower limb orthopedic surgery Exclusion criteria: Patient refusal to perform spinal anesthesia;?? failure to perform spinal anesthesia;?? ?body mass index more than 30??;?? history of the use of beta-blockers and alpha-2 ?agonists and calcium channel blockers;?? cardiovascular disease;?? pregnancy ?; ?coagulation disorders; localized infection in the spinal cord ;history of allergy to ?the drugs of dexmeditoimidine and clonidine and rupivacaine?;?? arrhythmia;?? ?psychological problems;?? peripheral and central homeopathy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: Every 15 minute to end of surgery. Method of measurement: Barometer.;Heart rate. Timepoint: Every 5 minute to end of surgery. Method of measurement: Count.;Oxygen saturation. Timepoint: Every 15 minute to end of surgery. Method of measurement: Percent.;Sensory block. Timepoint: Every 1 minute. Method of measurement: Pin prick method ?.;Motor block. Timepoint: Every 5 minute. Method of measurement: Bromeg scale.;Pain. Timepoint: In recovery and 1 and 2 and 4 and 6 and 12 hours after surgery?. Method of measurement: Visual Analogue Scale.	—

Measure

Time frame

Blood pressure. Timepoint: Every 15 minute to end of surgery. Method of measurement: Barometer.;Heart rate. Timepoint: Every 5 minute to end of surgery. Method of measurement: Count.;Oxygen saturation. Timepoint: Every 15 minute to end of surgery. Method of measurement: Percent.;Sensory block. Timepoint: Every 1 minute. Method of measurement: Pin prick method ?.;Motor block. Timepoint: Every 5 minute. Method of measurement: Bromeg scale.;Pain. Timepoint: In recovery and 1 and 2 and 4 and 6 and 12 hours after surgery?. Method of measurement: Visual Analogue Scale.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hesamodin Modir

Arak University of Medical Sciences

modir.he@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 19, 2026