Candida vulvovaginitis. Candidiasis of vulva and vagina
Conditions
Interventions
Intervention 1: Intervention group: Vaginal cream 2% of aqueous extract of Achillea millefolium, one applicator at night for 7 nights. Made in Pharmacy Department of Traditional Medicine, College of T
Tehran, IRAN. One applicator at night for 7 nights.
Treatment - Drugs
Intervention group: Vaginal cream 2% of aqueous extract of Achillea millefolium, one applicator at night for 7 nights. Made in Pharmacy Department of Traditional Medicine, College of Traditional Medic
Control group: Vaginal cream of clotrimazol 1% made by the PARS DAROU pharmaceutical company
Sponsors
Vice chancellor for research Babol University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: married women,18 to 45 years old The presence of sign and symptoms of candida vulvovaginitis Positive smear from vaginal discharge for candida Positive culture of vaginal discharge for candida
Exclusion criteria
Exclusion criteria: History of allergy to clotrimazole vaginal cream History of drug allergy Pregnancy Mensturation period Breastfeeding Menopause The presence of chronic underlying diseases: kidney, liver and Heart diseases, Diabetes and Immune deficiency Score 24-30 based on DLQI questionnaire Vulvar erythem score 3 Use of systemic antibiotics, immunosuppressive drugs or other vaginal creams and antifungal drugs during the past 4 weeks Patient's unsatisfactory to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Burning. Timepoint: At first, 7-10 days after the beginning of interventon and 2-3 weeks after the end of intervention. Method of measurement: Evauation of clinical symptom's remission (burning) with Dermatology Quality of Life Index (DLQI ) questionnaire.;Pruritus. Timepoint: At first, 7-10 days after the begining of interventon and 2-3 weeks after the end of intervention. Method of measurement: Evauation of clinical symptom's remission (pruritus) with Dermatology Quality of Life Index (DLQI ) questionnaire.;Dysparonia. Timepoint: At first, 7-10days after the begining of interventon and 2-3 weeks at the end of intervention. Method of measurement: Evauation the rate of satisfactory from intercourse with Dermatology Quality of Life Index (DLQI ) questionnaire.;Volvar erythema. Timepoint: At first, 7-10days after the begining of interventon and 2-3 weeks at the end of intervention. Method of measurement: Vulvar examination and scoring the erythema of vulva by Gynecologist. | — |
Secondary
| Measure | Time frame |
|---|---|
| Result of culture. Timepoint: At first, 7-10 days after the begining of intervention and 2-3 weeks after the end of intervention. Method of measurement: Sampling from vaginal discharges. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSomaye Zakerii
Babol Univesity of Medical Sciences
Outcome results
None listed