Skip to content

Study of combination therapy by oral isotretinoin, local clobetasol, and tacrolimus in comparison to local clobetasol, and tacrolimus on patients with Frontal Fibrosing Alopecia

Study of combination therapy by oral isotretinoin, local clobetasol, and tacrolimus in comparison to local clobetasol, and tacrolimus on patients with Frontal Fibrosing Alopecia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017091736173N1
Enrollment
34
Registered
2017-10-25
Start date
2017-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Frontal Fibrosing Alopecia. Lichen planopilaris

Interventions

in the first group the first 2 weeks of intervention includes local daily clobetasol for 5 days then local tacrolimus daily for 2 days, at the end of second week the patient will apply local daily tac
Treatment - Drugs

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients with clinicopathologically proven FFA, older than 18 years Exclusion criteria: 1. pregnancy 2. inability to participate or follow the trial 3. severe hypertriglyceridemia 4. liver enzyme disturbance 5. consumption of immunosuppressant or another kind of LLP or FFA therapies during recent 3 months

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Frontal Fibrosing Alopecia Severity Index (FFASI). Timepoint: before trial and in 2, 4, and 6 months later. Method of measurement: Questionaire.;Hair amount and density. Timepoint: before trial and in 2, 4, and 6 months later. Method of measurement: Fotofinder.;Clinical presentations (itching and irritation). Timepoint: before trial and in 2, 4, and 6 months later. Method of measurement: Patient asking.

Secondary

MeasureTime frame
Perifollicular scaling. Timepoint: before trial and in 2, 4, and 6 months later. Method of measurement: Trichoscope.;Perifulicular erythema. Timepoint: before trial and in 2, 4, and 6 months later. Method of measurement: Trichoscope.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Amini

Tehran University of Medical Sciences

Flipopart@gmail.com+98 21 5563 0223

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 18, 2026