Dental pulp histological respond to MTA, CEM and BIODENTIN

Clinical trial t compare the effect of CEM, MTA and Biodentin on dental pulp's histological response in orthodontic patients undergoing tooth extraction.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017091728804N2

Enrollment

Registered

2017-11-18

Start date

2017-10-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulpitis. Pulpitis

Interventions

Intervention 1: Intervention group 1: Placing Biodontin (Septodent Inc.) on prepared cavity near the pulp of premolar teeth according to manufacturer recommended procedure. Intervention 2: Interventio

Treatment - Other

Intervention group 1: Placing Biodontin (Septodent Inc.) on prepared cavity near the pulp of premolar teeth according to manufacturer recommended procedure.

Intervention group 2: Placing MTA (Angelus Inc.) on prepared cavity near the pulp of premolar teeth according to manufacturer recommended procedure.

Intervention group 3: Placing CEM (Yektazist dandan Inc.) on prepared cavity near the pulp of premolar teeth according to manufacturer recommended procedure.

Control group: no procedure is going to be done.

Eligibility

Sex/Gender

All

Age

14 Years to 25 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: human premolars; no fillings; cervical erosion; caries; teeth that are going to be extracted for orthodontic treatment; both gender; 14 - 25 years of age. Exclusion criteria: previous caries; filling; history of trauma; periodontal disease; severe pain; need to early extraction; unwillingness to cooperate.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Inflammation type. Timepoint: 6 weeks after intervention. Method of measurement: Measurement on pathology slide.;Formation of odontoblast cell. Timepoint: 6 weeks after intervention. Method of measurement: Measurement on pathology slide.;Width of dentin bridge. Timepoint: 6 weeks after intervention. Method of measurement: Measurement on pathology slide.;Forming dentin bridge. Timepoint: 6 weeks after intervention. Method of measurement: Measurement on pathology slide.;Necrosis. Timepoint: 6 weeks after intervention. Method of measurement: Measurement on pathology slide.;Severity of inflammation. Timepoint: 6 weeks after intervention. Method of measurement: Measurement on pathology slide.;Extent of inflammation. Timepoint: 6 weeks after intervention. Method of measurement: Measurement on pathology slide.	—

Measure

Time frame

Inflammation type. Timepoint: 6 weeks after intervention. Method of measurement: Measurement on pathology slide.;Formation of odontoblast cell. Timepoint: 6 weeks after intervention. Method of measurement: Measurement on pathology slide.;Width of dentin bridge. Timepoint: 6 weeks after intervention. Method of measurement: Measurement on pathology slide.;Forming dentin bridge. Timepoint: 6 weeks after intervention. Method of measurement: Measurement on pathology slide.;Necrosis. Timepoint: 6 weeks after intervention. Method of measurement: Measurement on pathology slide.;Severity of inflammation. Timepoint: 6 weeks after intervention. Method of measurement: Measurement on pathology slide.;Extent of inflammation. Timepoint: 6 weeks after intervention. Method of measurement: Measurement on pathology slide.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElina Rahminian.

Operative dentistry division of Kerman Dentistry University.

elinaa.er@gmail.com+98 34 3211 9021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026