The effect of N-acethylcystein and Selenium on thyroid function

The effect of selenium and N-acethylcystein on thyroid function tests in hemodialysis patients

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170917036224N3

Enrollment

Registered

2018-02-17

Start date

2017-11-22

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CKD,on dialysis. Chronic kidney disease, stage 5

Interventions

Intervention 1: The first group receives NAC 600 mg daily and Selenium 200 mg daily for 12weeks. Intervention 2: second group NAC 600 mg daily and Selenium placebo for 12 week. Intervention 3: Third

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Extremely high Thyroid stimulating hormon is greater than 10 and less than 0.1 Thyroid stimulating hormon All hemodialysis patients who under dialysis at least 6 months Patients' satisfaction with entering the study The absence of acute renal failure

Exclusion criteria

Exclusion criteria: antioxidant consumption any infection during the study (Catheter infection, urinary tract infection, etc) getting cancer thyroid disease N-acethylcystein consumption of selenium-containing compounds taking thyroid hormones

Design outcomes

Primary

Measure	Time frame
Thyroid function test TSH,T3,FT4. Timepoint: befor and after 12 week. Method of measurement: blood sample ,C.L.I.A.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Shahraki

Zahedan University of Medical Sciences

shahrakie@gmail.com+98 54 3329 5573

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026