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effect of Menaquinone(MK-7) supplementation on deppression status in patients with polycystic ovary syndrome

Effect of Menaquinone(MK-7) supplementation on deppression status, fasting blood sugar and serum vitamin K level in patients with polycystic ovary syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170916036204N5
Enrollment
84
Registered
2018-06-06
Start date
2017-06-22
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome. Polycystic ovarian syndrome

Interventions

Intervention 1: Intervention group: A capsule containing 90 µg of menaquinone daily for 8 weeks. Intervention 2: control group: A capsule containing avesil daily for 8 weeks.

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Suffering from polycystic ovary syndrome based on Rotterdam criteria; Age between 18 to 40

Exclusion criteria

Exclusion criteria: Unwillingness to participate Any disease or physiological changes that requires special treatment Pregnancy or lactation Using antidiabetic, antihypertensives, antihyperlipidemics or anticoagulant treatment Using metformin 2 months before entering the study and during the intervention; Acute or chronic inflammation Being smoker or/and alcoholic. Using drugs effective on bone metabolism Any current diet or supplement treatment Using oral contraceptives

Design outcomes

Primary

MeasureTime frame
Depression score in BECK questionnaire. Timepoint: Before and after the intervention. Method of measurement: BECK depression questionnaire.

Secondary

MeasureTime frame
Serum vitamin K level. Timepoint: Before and after the intervention. Method of measurement: ELISA kit.;Fasting Blood Sugar. Timepoint: Before and after intervention. Method of measurement: auto analyser.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFiroozeh Tarkesh

Shiraz University of Medical Sciences

firoozeh_tarkesh@yahoo.com+98 71 3725 1001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 11, 2026