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Effects of Dehydroepiandrosterone on ovary.

Study the effect of Dehydroepiandrosterone on the ovarian reserve rates and serum anti-Mullerian hormone levels in infertile women with diminished ovarian reserve.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017091529374N1
Enrollment
70
Registered
2017-09-15
Start date
2017-05-27
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diseases of the genitourinary system. Female infertility

Interventions

Intervention 1: Intervention group: Use of Dehydroepiandrosterone tablet, 25 mg three times a day till 6 weeks. Intervention 2: Control group: No treatment.
Treatment - Drugs
Intervention group: Use of Dehydroepiandrosterone tablet, 25 mg three times a day till 6 weeks.

Sponsors

Vice chancellor of Mazandaran University of Medical Science.
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Infertile women aged 20 to 45 years; normal hysterosalpingography; AMH levels < 1.5 ng/ml; antral follicular counts (AFC) < 7 in both ovaries; prior less than three failed in vitro fertilization cycles. Exclusion criteria: Normal ovarian response in ovulatory cycles or in vitro fertilization cycles.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Anti-mullerian hormone rate. Timepoint: Before intervention, six weeks after intervention. Method of measurement: Laboratory kits.;Clinical pregnancy rates. Timepoint: Forth weeks after embryo transfer. Method of measurement: Questionnare.

Secondary

MeasureTime frame
Miscarriage rates. Timepoint: Till twenty weeks after embryo transfer. Method of measurement: File.;Antral Follicular counts. Timepoint: Before treatment, six weeks after treatments. Method of measurement: ultrasonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarzieh Zamaniyan

Infertility Center, Department of Obstetrics and Gynecology, Mazandaran University of Medical Scienc

marziehzamaniyan@gmail.com+98 11 3336 5724

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026