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The effect of oral magnesium sulfate in asthma

The effect of oral magnesium sulfate on moderate and severe asthmatic attack in children aged 5-12 years old referred to emergency department of Ghaem Hospital

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170915036192N2
Enrollment
40
Registered
2018-11-27
Start date
2015-08-23
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

astma. Asthm

Interventions

Intervention 1: Intervention group: 300 mg capsules of magnesium sulfate were given to patients in this group every 12 hours for 5 days. Intervention 2: Control group: Placebo capsules with the same

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 12 Years

Inclusion criteria

Inclusion criteria: Asthma attack diagnosis based on history and clinical examination of patients diagnosed asthma by asthma specialist.modrate and severe asthma attacks in asthmatic children aged 5 to 12 years. The consent of the child and his legal guardian to enter the study.

Exclusion criteria

Exclusion criteria: Exclusion criteria: Mild asthma attacks that could be treated on an outpatient basis and at home. The presence of other chronic underlying conditions other than asthma, such as heart disease, renal or pulmonary disease. The use of drugs that affects the magnesium absorption and secretion mechanism include diuretics, digoxin, calcium supplements. Failure to use the drug by the patient and lack of proper follow up by the parent. Severe complications of the drug

Design outcomes

Secondary

MeasureTime frame
The speed of symptom improvement. Timepoint: When visiting, after 2 hours, 6 hours and 24 hours of referral, and then daily for up to 5 days. Method of measurement: questionnaire.

Primary

MeasureTime frame
Improve the symptoms of asthma. Timepoint: At the time of visit, 2,6,24 hours after the visit, and daily for up to 5 days. Method of measurement: quetionnary.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMelika Zarei Sani

Mashhad University of Medical Sciences

zareism931@mums.ac.ir+98 51 3882 8888

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026