Breast cancer. Breast, unspecified
Conditions
Interventions
a detectable marker will be inserted under the guide of sonography in the tumor. Afterwards, the patients will receive neoadjuvant chemotherapy based on the standards of the treating institute. Before
Treatment - Devices
Sponsors
Vice-chancellery for Research of Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Women between 30 and 70 years old; informed consent for participation; pathologic confirmation of invasive ductal carcinoma of breast; tumor stages of T3N1M0, T3N0M0, T2N1M0, and T2N0M0 based on classification of American Joint Committee on Cancer; and operable breast cancer patient who is candidate for breast conserving surgery. Exclusion criteria: Pregnancy and breast feeding; active collagen vascular diseases like scleroderma; history of chest wall radiotherapy for Hodgkin lymphoma; multifocal breast cancer in two separate quadrants of breast; presence of metastasis during treatment; and poor clinical response to the neoadjuvant chemotherapy.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Two-year disease-free survival. Timepoint: every 3 months. Method of measurement: physical examination and mammography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Dermatitis. Timepoint: every 3 months in the first two years; every 6 months in the third to fifth years after intervention. Method of measurement: physical examination.;Skin necrosis. Timepoint: every 3 months in the first two years; every 6 months in the third to fifth years after intervention. Method of measurement: physical examination.;Beauty. Timepoint: every 3 months in the first two years; every 6 months in the third to fifth years after intervention. Method of measurement: physical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Alireza Keramati
Omid Hospital
Outcome results
None listed