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The Comparison of two methods of endotracheal tube cuff pressure regulation on atelectasis in patients under mechanical ventilation

Comparing the effect of two endotracheal tube cuff inflation methods on the air leackage and atelectasia frequency in undergoing CABG.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017091319677N4
Enrollment
220
Registered
2017-10-15
Start date
2017-09-16
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atelectasis. Pulmonary collapse

Interventions

Intervention 1: Intervention group:after transferring the patient from operation room to ICU ,after stabilization of patient's hemodynamic condition ,air leakage from endotracheal cuff will be examine
Prevention
Intervention group:after transferring the patient from operation room to ICU ,after stabilization of patient's hemodynamic condition ,air leakage from endotracheal cuff will be examined and resolved b
Control group:Intervention group:after transferring the patient from operation room to ICU ,after stabilization of patient's hemodynamic condition ,air leakage from endotracheal cuff will be examined

Sponsors

Vice Chancellor for Research Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: age above 18 ; normal BMI (18.5-24.9) ; intubated through endotracheal tube (orotracheal) ;patients under mechanical ventilation and open heart surgery and CABG; FEV1/FVC > 0.7 (based on spirometery);chest x ray (based on radiologist's diagnosis) and history and examination(by Heart anesthetist)not to mention to acute or chronic pulmonary disease; heart failure ; immunodeficiency ;absence of chronic pulmonary disease(COPD) ; asthma ;patients with severe valve failure ; laryngeal disease or laryngeal anomalies. Exclusion criteria: Patients with difficult intubation in 2 or more than 2 try ; reoperation due to post surgery critical condition ( more than 1000 cc drainage ; heart tamponade ) ; history of Pulmonary diseases in last 2 months.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Air leackage and atelectasis. Timepoint: 24 hours after the intervention. Method of measurement: auscultation.

Secondary

MeasureTime frame
Endotracheal cuff pressure with volume-time curve technique. Timepoint: after admition to ICU and hemodynamic stabilization and temperture 35.5 , 37 with 20 minute interval. Method of measurement: Pressure gauge manometer.;Endotracheal cuff pressure without any audible sound of air leakkage technique. Timepoint: after admition to ICU and hemodynamic stabilization and temperture 35.5 , 37 with 20 minute interval. Method of measurement: Pressure gauge manometer.;Arterial oxygen pressure. Timepoint: 20 minute after extubation. Method of measurement: Arterial blood gas test(ABG).;Cross clamp time. Timepoint: during surgery. Method of measurement: Clock Gauge.;Body tempreture. Timepoint: after admition to ICU and 3 times after surgery in 20 minute intervals. Method of measurement: termometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeed Jafari

Mazandaran University of Medical Sciences - School of Nursing and Midwifery Nusseibeh

doctor182000@yahoo.com00

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026