Comparative study of the impact of infusion Apotel and Ketorolac in reducing postoperative pain and opioid consumption in patients undergoing orthopedic surgery of the lower limbs.

Comparative study of the impact of infusion Apotel and Ketorolac in reducing postoperative pain and opioid consumption in patients undergoing orthopedic surgery of lower limbs.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017091231642N2

Enrollment

Registered

2017-11-18

Start date

2017-09-12

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain of orthopedic surgery. Other acute postprocedural pain.

Interventions

Intervention 1: After orthopedic surgery of lower limbs, In first group, we use

Ampul Apotel 1 gr IV per 6 hours. Intervention 2: In secound group of this study Ampul Ketorolac 90 mg in 1 lit Serum N/S infused.

Treatment - Drugs

After orthopedic surgery of lower limbs, In first group, we use

Ampul Apotel 1 gr IV per 6 hours.

In secound group of this study Ampul Ketorolac 90 mg in 1 lit Serum N/S infused.

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Entry criteria: age 20-60 ; Score pain less than 8 Exit criteria: history of cardiovascular disease ; renal disease ; treatment with warfarin ; pregnant women

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Receive pain medication. Timepoint: 24 hours study. Method of measurement: Receiving an analgesic.;Pain. Timepoint: 12 and 24 hours after surgery. Method of measurement: Visual Analoge Scale(VAS) system.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMina Mirzaei

Ardebil University of Medical Sciences.

minamirzai29@yahoo.com+98 45 3324 1135

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026