Effects of two different types of crystalloid infusion after kidney transplantation

A comparative study of effect of equal ringer’s lactate and normal saline solution infusion versus normal saline on acid–base balance and serum electrolytes after living-related renal transplantation

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170910036107N4

Enrollment

Registered

2019-04-10

Start date

2017-07-16

Completion date

Unknown

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal transplantation. Kidney transplant status

Interventions

Intervention 1: Intervention group: infusion of equal ringer’s lactate and normal saline solution during renal transplantation surgery to maintain systolic pressure variation between 5-15 mmHg. Interv

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients undergoing living donor renal transplantation due to end-stage renal disease Patients aged 18-70 years

Exclusion criteria

Exclusion criteria: Severe cardiovascular disease Preoperative hyperkalemia of > 5.5 mEq/L Using a blood transfusion during renal transplantation Metabolic acidosis with pH < 7.2 Dialysis after the surgery The duration of the operation more than four hours Deceased renal donor

Design outcomes

Primary

Measure	Time frame
Arterial blood gas test. Timepoint: Before surgery and immediately after surgery. Method of measurement: Arterial blood sample.;Blood urea nitrogen. Timepoint: Before surgery, immediately after surgery and 3 and 7 days after surgery. Method of measurement: Arterial blood sample.;Serum Creatinine. Timepoint: Before surgery, immediately after surgery and 3 and 7 days after surgery. Method of measurement: Arterial blood sample.;Serum sodium. Timepoint: Before surgery and immediately after surgery. Method of measurement: Arterial blood sample.;Serum potassium. Timepoint: Before surgery and immediately after surgery. Method of measurement: Arterial blood sample.	—

Measure

Time frame

Arterial blood gas test. Timepoint: Before surgery and immediately after surgery. Method of measurement: Arterial blood sample.;Blood urea nitrogen. Timepoint: Before surgery, immediately after surgery and 3 and 7 days after surgery. Method of measurement: Arterial blood sample.;Serum Creatinine. Timepoint: Before surgery, immediately after surgery and 3 and 7 days after surgery. Method of measurement: Arterial blood sample.;Serum sodium. Timepoint: Before surgery and immediately after surgery. Method of measurement: Arterial blood sample.;Serum potassium. Timepoint: Before surgery and immediately after surgery. Method of measurement: Arterial blood sample.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSarah Faghfuri

Iran University of Medical Sciences

Sarah.f12065@gmail.com+98 21 8116 1532

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026