Menorrhagia. excessive and frequent menstruation with regular cycle
Conditions
Interventions
Intervention 1: Intervention 1. A 250 mg capsule extract of pomegranate peel is consumed after each meal in 7 days of menstruation for three cycles. Intervention 2: Intervention 1. A 250 mg capsule of
Treatment - Drugs
Intervention 1. A 250 mg capsule extract of pomegranate peel is consumed after each meal in 7 days of menstruation for three cycles.
Intervention 1. A 250 mg capsule of Mefenamic Acid is consumed after each meal in 7 days of menstruation for three cycles.
Sponsors
Shahed University
Eligibility
Sex/Gender
Female
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients with high or long uterine bleeding who have had a negative pregnancy test; and are not breast-feeding; in ultrasonography their thickness of endometrium is normal; there is no mass of adnexa and ovaries except for a simple cyst less than two centimeters; genecology examination and Pap smear tests are normal; they’re not taking other hormonal and anticoagulant drugs like aspirin; or herbal drugs and teas; they do not have systemic or organic diseases and bleeding disorders; In the ultrasound the size of the uterus is less than 10 cm; there is no submucosal or intramural fibroma; and sub-serous fibroma is not bigger than 4 cm; they do not use IUD; and do not have BMI greater than 30; CBC and Hb are not less than 10. Exclusion criteria: Taking hormonal drugs during the study; experiencing possible side effects like anemia (Hb less than 10); needing surgery or other interventions; leaving the study on personal requests; requiring emergency procedures during the study due to severe bleeding; occurrence of pregnancy; and experiencing serious side effects due to the drugs.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding Volume. Timepoint: One month before, first, second and third month after intervention. Method of measurement: Pictorial Blood Loss Assessment Chart.;Bleeding Volume. Timepoint: One month before, first, second and third month after intervention. Method of measurement: Pictorial Blood Loss Assessment Chart. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hb level. Timepoint: Before and 3 months after intervention. Method of measurement: Lab test.;Quality of life. Timepoint: Before and 3 months after intervention. Method of measurement: Menorrhagia questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGholamreza Salsali
Shahed University
Outcome results
None listed