hypothyroidism. Hypothyroidism, unspecified
Conditions
Interventions
Intervention 1: Dietary Zinc supplement, 30 mg/d? Dietary vitamin A supplement, 25000 IU twice a week and Dietary magnesium supplement, 250 mg/d for 10 weeks. Intervention 2: Placebo, the same as zinc
Treatment - Other
Placebo
Dietary Zinc supplement, 30 mg/d? Dietary vitamin A supplement, 25000 IU twice a week and Dietary magnesium supplement, 250 mg/d for 10 weeks
Placebo, the same as zinc tablet as the active supplement with the same size, daily for 10 weeks? Placebo, the same as magnesium tablet as the active supplement with the same size, daily for 10 weeks
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: Hypothyroid patients referring to Endocrine and Metabolism Research Institute of Iran University of Medical Sciences who have the following criteria and express their willingness to cooperate. Inclusion criteria: patients consensus; age 20 to 65 years old; BMI < 30 kg/m2; Drug therapy with levothyroxine; Exclusion Criteria: Unwillingness to continue the study; compliance below the 80 percent; having history of Diabetes; Hypertension; cardiovascular diseases; gastrointestinal diseases; anemia; pregnant or lactating women; alcohol consumer or Cigarette smoker, Taking any supplements including vitamins & minerals in last 3 months; digestive complications for supplements; Changing the dosage of the drug in the study
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thyroid Hormones. Timepoint: Before intervention and 10 weeks after intervention. Method of measurement: ELIZA. | — |
Secondary
| Measure | Time frame |
|---|---|
| MDA. Timepoint: Before intervention and 10 weeks after intervention. Method of measurement: measurement kit.;Hs-CRP. Timepoint: Before intervention and10 weeks after intervention. Method of measurement: ELIZA.;Body Composition. Timepoint: Before intervention and 10 weeks after intervention. Method of measurement: Body Composition Analyser.;Basal Metabolic Rate. Timepoint: Before intervention and 10 weeks after intervention. Method of measurement: Body Composition Analyser.;TAC. Timepoint: Before intervention and 10 weeks after intervention. Method of measurement: measurement kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mohammad Reza Vafa
Iran University of Medical Sciences
Outcome results
None listed