The effect of Levothyroxine on the infant development status in pregnant women with subclinical hypothyroidism

Assessment of the effect of Levothyroxine on the infant development status in pregnant women with subclinical hypothyroidism

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017090314849N5

Enrollment

1600

Registered

2017-09-11

Start date

2017-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subclinical hypothyroidism. Subclinical iodine-deficiency hypothyroidism

Interventions

Intervention group will treat with Levoxine (Levothyroxine sodium). These patients will receive 1 mg per kg of body weight daily levothyroxine. Dosages will maintain throughout pregnancy until deliver

Treatment - Drugs

Eligibility

Sex/Gender

Female

Age

15 Years to 46 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: pregnant women during the first 20 weeks of pregnancy. Exclusion criteria: multiple pregnancy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Gross motor developmental status. Timepoint: Since 4 months after birth. Method of measurement: Ages and Stages Questionnaire (ASQ).;Problem solving developmental status. Timepoint: Since 4 months after birth. Method of measurement: Ages and Stages Questionnaire (ASQ).;Fine motor developmental status. Timepoint: Since 4 months after birth. Method of measurement: Ages and Stages Questionnaire (ASQ).;Personal - social developmental status. Timepoint: Since 4 months after birth. Method of measurement: Ages and Stages Questionnaire (ASQ).;Communication developmental status. Timepoint: Since 4 months after birth. Method of measurement: Ages and Stages Questionnaire (ASQ).	—

Measure

Time frame

Gross motor developmental status. Timepoint: Since 4 months after birth. Method of measurement: Ages and Stages Questionnaire (ASQ).;Problem solving developmental status. Timepoint: Since 4 months after birth. Method of measurement: Ages and Stages Questionnaire (ASQ).;Fine motor developmental status. Timepoint: Since 4 months after birth. Method of measurement: Ages and Stages Questionnaire (ASQ).;Personal - social developmental status. Timepoint: Since 4 months after birth. Method of measurement: Ages and Stages Questionnaire (ASQ).;Communication developmental status. Timepoint: Since 4 months after birth. Method of measurement: Ages and Stages Questionnaire (ASQ).

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSima Nazarpour

Research Institute for Endocrine Sciences

snazarpour@gmail.com+98 21 2243 2500

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 4, 2026