Preparation, evaluation and comparison of two topical semisolid formulations containing insulin for improvement and acceleration of diabetic wound.

Preparation, evaluation, and comparison of two topical semisolid formulations containing insulin for improvement and acceleration of diabetic wound.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170903036045N2

Enrollment

Registered

2020-04-17

Start date

2020-03-10

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic wounds. Open wound of knee and lower leg

Interventions

Intervention group: 1) Wound should be washed with sterile NS or sterile water after wearing sterile gloves. 2) If there is any necrosis, debridement should be done gently by sterile gauze pads (wet w

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 Diabetic ulcer with at least 1 cm2 with grade II Wagner calcification Over 5 ABI Over 3 MDNS Willingness to participate in the study

Exclusion criteria

Exclusion criteria: Nursing and pregnant woman Immunosuppressive therapy Immunosuppressive disorder Kidney disorder (Cr>2.5) CHF, CABG, Cardiomyopathy HA1C>10 Smoking Alcohol and drugs Dermatitis Patients who received other treatments for their diabetic ulcers like antibiotic therapy Infectious diabetic wounds

Design outcomes

Primary

Measure	Time frame
Wound surface. Timepoint: Every weeks up to 12 weeks. Method of measurement: Ealipers.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.mohamad ali palar

Skin and leprosy center

mohammadali.palar@gmail.com+98 21 8896 3804

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026