Effect of using vaginal estrogen cream versus not using on endometrial thickness in infertile women under embryonal transfer

Effect of using vaginal estrogen cream versus not using on endometrial thickness in infertile women under embryonal transfer: a single blind randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201708309014N180

Enrollment

100

Registered

2017-09-03

Start date

2016-08-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Intervention 1: Intervention group: Conjugate vaginal estrogen cream once a day for 11 days plus estradiol tablet 6 mg once a day for 11 days. Intervention 2: Control group: Estradiol tablet 6 mg once

Treatment - Drugs

Intervention group: Conjugate vaginal estrogen cream once a day for 11 days plus estradiol tablet 6 mg once a day for 11 days

Control group: Estradiol tablet 6 mg once a day for 11 days.

Eligibility

Sex/Gender

Female

Age

20 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age of 20 to 35 years; infertility. Exclusion criteria: Estradiol contraindication; uterus problem.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Measuring the endometrial thickness. Timepoint: before intervention and on 5 and 9 and 11 days of the menstrual cycle. Method of measurement: using sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazanin Sahebi

Fatemieh Hospital

nazaninsahebi@yahoo.com+98 81 3828 3939

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026