??Effect of GnRH-a in endometrial preparation for frozen-thawed embryo transfer cycles in patient with repeated implantation failure.

Effect of GnRH-a in endometrial preparation for frozen-thawed embryo transfer cycles in patient with repeated implantation failure.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201708292604N3

Enrollment

Registered

2017-09-18

Start date

2017-08-16

Completion date

Unknown

Last updated

2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

repeated implantation failure. complication associated with artificial fertilization ,unspecified

Interventions

Intervention 1: In case group , patients receive daily subcutaneous injections of 0.1 mg of GnRH-a( diphereline) starting from day 21 of previous cycles.The dose is reduce to 0.05 mg from the second

Eligibility

Sex/Gender

Female

Age

18 Years to 42 Years

Inclusion criteria

Inclusion criteria: infertile women with at least 2 previous failed implantation.

Exclusion criteria

Exclusion criteria: Endometrial polyp myoma uterine anomaly

Design outcomes

Primary

Measure	Time frame
Chemical pregnancy. Timepoint: 2 weeks after embryo transfer. Method of measurement: serum BHCG.;Clinical pregnancy. Timepoint: 2 wk after positive ß hCG. Method of measurement: the detection of a fetal heartbeat in sonography.;Implantation rate. Timepoint: 2 wk after positive ß hCG. Method of measurement: the number of gestational sacs per embryos transferred.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Robab Davar

Yazd Reproductive Sciences Institute

r_davar@yahoo.com+98 35 3824 7085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026