Comparison between the effect of two antibacterial gels on reducing the incidence of dry socket after wisdom teeth surgery

Comparison between the effect of CHX 0.2% gel and Ozone gel on preventing dry socket after mandibular third molar surgery.(clinical trial, randomized, double blind)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017082735916N1

Enrollment

Registered

2017-09-28

Start date

2016-08-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry Socket.

Interventions

Intervention 1: Intevention group Ozone Gel(O3LIFE,India). used after surgery and irrigation of socket, up to filling the socket. Intervention 2: Intevention group 0.2% Chlorhexidine gel (Periokin, B

Prevention

Placebo

Intevention group Ozone Gel(O3LIFE,India). used after surgery and irrigation of socket, up to filling the socket.

Intevention group 0.2% Chlorhexidine gel (Periokin, Barcelona, Spain). used after surgery and irrigation of socket, up to filling the socket.

control group vaseline(Petroleum Gel)(Sepidaj co, Iran) used after surgery and irrigation of socket, up to filling the socket.

Eligibility

Sex/Gender

Male

Age

15 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: man 15-60 years old; completely healthy in terms of systemic conditions (ASA I); at least one mandibular third molar with moderate difficulty; able to filling VAS questionnaire. exclusion criteria: History of smoking; Taking systemic antibiotics or taking antibiotics over the last 24 hours; The length of the surgical time is more than thirty minutes; Having any history of allergies; History of gastric ulcer or any digestive problem; Not attending follow-up meetings. Use of any other drugs as post-surgical medication; Mental inability to give informed consent.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Reducing the prevalevce of dry socket. Timepoint: third day after surgery (follow up). Method of measurement: postoperative pain in and around the extraction site, which increases in severity at any time between 1 and 3 days after the extraction accompanied by a partially or totally disintegrated blood clot within the alveolar socket with or without halitosis. It has been identified with the scale of Has / has not happened.;Decreasing the Severity of pain. Timepoint: from 1st to 7th days after surgery. Method of measurement: according to the VAS questionare.	—

Measure

Time frame

Reducing the prevalevce of dry socket. Timepoint: third day after surgery (follow up). Method of measurement: postoperative pain in and around the extraction site, which increases in severity at any time between 1 and 3 days after the extraction accompanied by a partially or totally disintegrated blood clot within the alveolar socket with or without halitosis. It has been identified with the scale of Has / has not happened.;Decreasing the Severity of pain. Timepoint: from 1st to 7th days after surgery. Method of measurement: according to the VAS questionare.

—

Secondary

Measure	Time frame
Any side effects after using each gels. Timepoint: during the first week after surgery. Method of measurement: patients had researcher's phone number to call if they had any problems or questions.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParisa Kohani

Qazvin University of Medical Sciences

parisa.kohani@gmail.com p.kohani@qums.ac.ir+98 28 3366 4931

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026