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Study of analgesic and anti-inflammatory effect of ginger

Comparison of analgesic and anti-inflammatory effect of topical application of ginger aqueous extract with local dexamethasone injection after extraction of mandibular wisdom teeth

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017082635906N1
Enrollment
50
Registered
2017-09-09
Start date
2017-09-06
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extracting the mandibular double-sided wisdom teeth.

Interventions

In this double-blind clinical trial, anti-inflammatory and anti-inflammatory effects of topical administration of a 20% tissue bioadhesive made of 100% ginger extract and a mucosal dexamethasone injec
Treatment - Drugs

Sponsors

The Vice-Chancellor of Research of Bushehr University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: The patient has a double-walled tooth (based on the angle of tooth placement in the jaw, the amount of bone and soft tissue on the tooth, the condition of the tooth in relation to the anterior border of ramus), the willingness to cooperate And there is no prohibition of tooth surgery or sensitivity to ginger. The tooth does not have any pathological lesions in the root zone in clinical and radiographic examinations. No other surgical procedures for at least two weeks. Exclusion criteria: kidney or liver disease, bleeding problems such as hemophilia, neutropenia, blood platelet deficiency, etc., previous or current stomach ulcers, any heart disease, Known allergies, allergies, or individual reactions to either the drugs used or the drugs that may be used in the study (ginger, lidocaine anesthesia, acetaminophen codine 300, gelofen 400, amoxicillin 500, and metronidazole 400 mg G) Pregnancy and lactation, taking analgesic or anti-inflammatory drugs 24 hours before the study, having pain and other inflammatory symptoms including swelling, high blood pressure and the inability to open the mouth before the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The amount of pain. Timepoint: Day of intervention, one day after intervention, two days after intervention, three days after intervention. Method of measurement: VAS scale (number).;Mouth opening rate. Timepoint: Pre-intervention, 24 hours after intervention, 72 hours after intervention. Method of measurement: Millimeters.;Distance between the corner of the mouth and the tragus. Timepoint: Pre-intervention, 24 hours after intervention, 72 hours after intervention. Method of measurement: Millimeters.;The amount of acetaminophen codoine 300 mg taken. Timepoint: Day of intervention, one day after intervention, two days after intervention, three days after intervention. Method of measurement: questionnaire.

Secondary

MeasureTime frame
Age. Timepoint: Before intervention. Method of measurement: questionnaire.;Gender. Timepoint: Before intervention. Method of measurement: questionnaire.;Infection. Timepoint: Before intervention, 24 hours after intervention, 72 hours after intervention. Method of measurement: View, interview.;Any other anti-inflammatory or analgesic drug. Timepoint: three days after the intervention. Method of measurement: questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSahar Zandi

School of Dentistry, Bushehr University of Medical Sciences

s.zandi@bpums.ac.irsaharzandi72@yahoo.com+98 77 3356 5374

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026