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Effect of misoprostol moistened with normal saline and acetic acid for second-trimester pregnancy termination.

Comparative study of effect of misoprostol moistened with normal saline and acetic acid for14 to 26 weeks pregnant women termination.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017082635898N1
Enrollment
Unknown
Registered
2017-10-17
Start date
2016-12-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Induce abortion of second trimester of pregnancy. Other and unspecified failed attempted abortion, without complication

Interventions

Intervention 1: Misoprostol(prostaglandin E1 analog) moistened with acetic acid, (tablet 200 microgram)400 microgram, 2tablets q4hour, maximum 5doses vaginaly adminestrated for intervention group
Treatment - Drugs
Misoprostol(prostaglandin E1 analog) moistened with acetic acid, (tablet 200 microgram)400 microgram, 2tablets q4hour, maximum 5doses vaginaly adminestrated for intervention group
Misoprostol (prostaglandin E1 analog) moistened with normal salin, (tablet 200 microgram)400 microgram, 2tablets q4hour, maximum 5doses vaginaly adminestrated for control group.

Sponsors

Vice chancellor for research, Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
9 Years to 50 Years

Inclusion criteria

Inclusion criteria: inclusion: pregnant women at 14 to 26 weeks of pregnancy who admitted for induced abortion with vaginal misoprostol. exclusion criteria :not respond to misoprostol;start of spontaneous abortion; contraindication of medical termination like previa placenta;prostaglandin contraindication like hyper sensivity,asthma, glucoma, cardiovascular disease.

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

MeasureTime frame
Induction interval to delivery. Timepoint: During 72 hours from intervention. Method of measurement: Questionnaire, hour.;Dose of misoprostol used to termination. Timepoint: During 72 hour from intervention. Method of measurement: Questionnaire.;Side effects, nausa, vomiting, shaking. Timepoint: During 48 hours from intervention. Method of measurement: Questionnaire, check list.—

Primary

MeasureTime frame
Success in termination of pregnancy at first 24 hours. Timepoint: Every 4 hour from intervention. Method of measurement: Questionnaire, hour.;Success in termination of pregnancy after first dose. Timepoint: Every 4 hours from intervention. Method of measurement: Questionnaire, hour.—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBibi Elham Rezaei Askariye

Mashhad University of Medical Sciences

rezaeiae921@mums.ac.ir; rezaeidrel@gmail.com; presidentoffice@mums.ac.ir+98 51 3601 4875

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026