Skip to content

Evaluation of the effect of oral Oxycodone and Saphenous nerve block in knee replacement surgery

Comparison of the Effect of Oral Oxycodone and Saphenous Nerve Block in Controlling the Acute Post-operative Pain in Patients Undergoing Knee Replacement Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170826035905N3
Enrollment
80
Registered
2018-11-21
Start date
2016-04-03
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Regional Anesthesia and Pain Management. Acute pain

Interventions

Intervention 1: In the first group, oral oxycodone was administered at a dose of 5 mg two hours before surgery and every six hours after operation based on patient request and presence of pain. Int

Sponsors

Baqiyatallah University of Medical Sciences/Trauma Research Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 75 Years

Inclusion criteria

Inclusion criteria: Age between 15 and 75 years Candidates for knee replacement surgery Classification for American Society of Anesthesiology (ASA) I, II (patients with normal or mild and controlled underlying disease).

Exclusion criteria

Exclusion criteria: Previous knee joint surgery Bilateral surgery Kidney or liver function disorders, History of allergic sensitization to non-steroidal anti-inflammatory drugs History of addiction History of chronic drug use for pain control History of severe cardiovascular or respiratory disease History of neurological disease with lower limb involvement History of gastrointestinal ulcer Failure of block

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 2,6,12,24 hours after surgery. Method of measurement: Visual Analog Scale.

Secondary

MeasureTime frame
Nausea. Timepoint: 2,6,12,24 hours after surgery. Method of measurement: Rating variable :Mild(0-1) Moderate(2-3) Severe(more than 3).;Sedation. Timepoint: 2,6,12,24 hours after surgery. Method of measurement: Rating variable :Mild(0-1) Moderate(2-3) Severe(more than 3).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNader Ali Nazemian Yazdi

Tehran University of Medical Sciences

drnnazemian@gmail.com+98 21 6676 0269

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026