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The Effect of Six-Week Aerobic Exercise and consumption of nano-curcumin on Interleukin 6, Interleukin 10, Tumor necrosis factor-alpha, Interleukin 1B, Brain-derived neurotrophic factor, Depression, Medium and short-term memory in 60-65 Years Old Women with metabolic syndrome.

The Effect of Six-Week Aerobic Exercise and consumption of nano-curcumin on Interleukin 6, Interleukin 10, Tumor necrosis factor-alpha, Interleukin 1B, Brain-derived neurotrophic factor, Depression, Medium and short-term memory in 60-65 Years Old Women with metabolic syndrome.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017082335857N1
Enrollment
44
Registered
2017-11-16
Start date
2017-07-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

syndrome metabolic. ---------------

Interventions

Intervention 1: Intervention group: Drug group, nano-curcumin was taken once a day (morning) pill - 80 mg for six weeks. The nano-curcumin manufacturing license used in the study was for the Exquisite
Treatment - Drugs
Treatment - Other
Intervention group: Drug group, nano-curcumin was taken once a day (morning) pill - 80 mg for six weeks. The nano-curcumin manufacturing license used in the study was for the Exquisite Nano Sina Compa
Intervention group: Exercise and Drug group, six-week aerobic exercise with moderate intensity during the first week MECU group and ME participated in three sets of twelve-minute aerobic exercise trai
Intervention group: Exercise group, six-week aerobic exercises with moderate intensity During the first week MECU group and ME participated in three sets of twelve-minute aerobic exercise training wit
Control group: This group did not received any interventions within 6 weeks of the study.

Sponsors

Vice chancellor for reserch of University of Bonab
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
60 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Being female; Being 60-65 years old; and metabolic syndrome; Not doing regular exercise. Exclusion criteria: Being absent for 3 sessions during 6 weeks; Not consuming (nano-curcumin) according to the instructions.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
IL6. Timepoint: Before intervention and after six week intervention. Method of measurement: pg- Enzyme-linked Immunosorbent Assay.;IL10. Timepoint: Before intervention and after six week intervention. Method of measurement: pg- Enzyme-linked Immunosorbent Assay.;IL1B. Timepoint: Before intervention and after six week intervention. Method of measurement: pg- Enzyme-linked Immunosorbent Assay.;TNF-a. Timepoint: Before intervention and after six week intervention. Method of measurement: pg- Enzyme-linked Immunosorbent Assay.;BDNF. Timepoint: Before intervention and after six week intervention. Method of measurement: pg- Enzyme-linked Immunosorbent Assay.—

Secondary

MeasureTime frame
Short-Term Memory. Timepoint: Before intervention and after six week intervention. Method of measurement: Powerpoint Software-Recall Numbers Test.;Medium-Term Memory. Timepoint: Before intervention and after six week intervention. Method of measurement: Powerpoint Software-Picture Recall Test.;Depression. Timepoint: Before intervention and after six week intervention. Method of measurement: Beck Depression Test- Questionnaire.—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Karim Azali Alamdari

Azarbaijan Shahid Madani

azalof@yahoo.com; azalof@gmail.com; azaiof@yahoo.com;+98 41 3772 4829

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 27, 2026