Preeclampsia. Eclampsia in pregnancy
Conditions
Interventions
Intervention 1: The intervention group received 12 mg Betamethasone in two doses every 24 hours plus prescribed 40 mg osmoparazole daily. Intervention 2: The control group received 12 mg Betamethasone
Treatment - Drugs
Placebo
The intervention group received 12 mg Betamethasone in two doses every 24 hours plus prescribed 40 mg osmoparazole daily.
The control group received 12 mg Betamethasone in two doses every 24 hours plus prescribed 40 mg placebo daily.
Sponsors
Vice chancellor for research, Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Preeclampsia diagnosis; hypertensive pregnancy; gestational age between 26 to 32 weeks; single-crowned pregnancy; no need to terminate the pregnancy in the next 48 hours; absence of anomalies in the fetus; patient satisfaction for expected treatment; Exclusion criteria: Eclampsia; uncontrolled blood pressure; pulmonary edema; cerebrovascular accidents; heart failure; HELLP syndrome; use of proton pump inhibitors; renal failure; uncertain tests for the evaluation of embryo's health
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of admission to delivery. Timepoint: before intervention until delivery. Method of measurement: Pregnancy termination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Frequency of maternal and fetal complications in patients with preeclampsia. Timepoint: before intervention until delivery. Method of measurement: Questionnaire and checklist.;Biomarker level of tyrosine kinase and endoglycine. Timepoint: after Intervention. Method of measurement: Blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Shourvarzi
Mashhad University of Medical Sciences
Outcome results
None listed