Immunogenicity of fIPV against the usual IM injection of IPV. Need for immunization against poliomyelitis
Conditions
Interventions
Intervention 1: First Intervention group:Inoculation of 0.1 ml of fIPV subcutaneously at 2nd and 4th months of life, in addition to the routine immunization schedule. Intervention 2: Control Group: On
Treatment - Drugs
First Intervention group:Inoculation of 0.1 ml of fIPV subcutaneously at 2nd and 4th months of life, in addition to the routine immunization schedule.
Control Group: Only routine immunization schedule.
Second Intervention group: Inoculation of 0.5 ml of intramuscular IPV at 4th month of life, in addition to routine immunization schedule.
Sponsors
Vaccin Preventable Diseases Department; Ministry of Heath; I.R. Iran
Eligibility
Sex/Gender
All
Age
2 Months to 2 Months
Inclusion criteria
Inclusion criteria: Inclusion criteria: Consent of parents for taking part of their infants; Completeness of all vaccines that an infant have had to receive within the first two months of life; Absence of any contraindication for receiving all the vaccines which are in common use in the national immunization system of I. R . Iran.; Residence up to the end of age 8 months of the participants in the study region; nationality should be Iran.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Appearence of anti-Polio antibodies against Poliovirus types 1 and 3. Timepoint: end of 7th month of age. Method of measurement: Measurement of antibody levels using ELISA methods. | — |
Secondary
| Measure | Time frame |
|---|---|
| The most common vaccination complications. Timepoint: Up to the 7th months of age. Method of measurement: Monitoring of signs and sypmtoms. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShahrokh Izadi
Zahedan University of Medical Sciences
Outcome results
None listed