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Comparison of two methods heparin infusion, intermittent intravenous injection and continuous infusion in patients with Acute Coronary Syndrome Disease

Comparison Study of heparin injection by using intermittent intravenous injection and Continuous Infusion Syringe Pump , on APTT results and possible side effects in patients with acute coronary syndrome (ACS), in 22 Bahman Hospital of Neishabour

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170822035849N4
Enrollment
60
Registered
2018-04-15
Start date
2017-07-23
Completion date
Unknown
Last updated
2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute coronary syndrome. acute ischemic heart diseases

Interventions

Intervention 1: In this study, the patients were divided into two groups of 30, randomly divided into: 1) intervention group: In the intervention group, the administration of heparin, based on the hal

Sponsors

Sabzevar University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients with acute coronary syndrome according to the cardiologist's diagnosis 2- Conscious and informed consent of patients to participate in the study. 3-Being age in the range of 50 to 75 years

Exclusion criteria

Exclusion criteria: 1. History of bleeding ulcers, especially in the gastrointestinal tract 2. The presence of active bleeding accompanied by discoloration of the blood, or a tendency to bleeding like hemophilia, thrombocytopenia, blood cancers 4. Suspicious cases of intracranial bleeding 4.The presence of suspected cases of intracranial hemorrhage 5. Suppurative thrombophlebitis 6. Wounded injuries or the massive loss of skin 7. Subacute endocarditis 8.The presence of renal failure 9. High blood pressure 160 /90 and resistant to treatment 10. Recent eye surgery or spinal cord 11. Higher rang of INR (more than 3.5 )and a platelet below 100,000 12. Having an APTT of more than 100

Design outcomes

Primary

MeasureTime frame
Activated Partial Thromboplastin Time. Timepoint: By starting heparin injection, sampling has done at every 6 hours, which in 48 hours we have 8 samples for each of patients. Method of measurement: The first, blood sample is taken from the patient, and then poured into an APTT tube and transferred to the lab for testing.

Secondary

MeasureTime frame
Platelets. Timepoint: Before starting heparin in both ways. Method of measurement: Blood platelets measurement.;The Bleeding. Timepoint: At least every 6 hours as well as if needed. Method of measurement: The measuring instrument are tests, clinical examination and biographies.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Saneipour

Sabzevar University of Medical Sciences

nurse.sanei@gmail.com+98 51 43304

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026