Acute lymphoblastic leukaemia [ALL].
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ALL diagnosis based on the criteria of the International Institute of Cancer with initial involvement of more than 20% of bone marrow Hepatotoxicity of Grade 2 and 3 in each of the following four cases based on the criteria of the International Institute of Cancer: Aminoalanine Transferase (ALT); Aspartate Aminotransferase (AST); Total Bilirubin (TB) ALL patients in the chemotherapy maintenance phase. ALL patients, 15-2 years old Patients ALL Pre Bcell, Early Pre Bcell
Exclusion criteria
Exclusion criteria: Unwillingness to participate in the studyl Extra bile duct obstruction, severe liver or kidney failure, gastrointestinal obstruction, malabsorption syndrome, viral hepatitis Grade 4 hepatotoxicity Sepsis-induced hepatotoxicity Intolerance to Oral Fluoride Deny the patient to study and continue taking the medication No regular and daily intake of medication Gastritis and other complications associated with taking Lourgal History of allergy due to previous use of loroge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver Enzyme (AST ALT Bill Total & Direct). Timepoint: Befor Intervention , 35 and 70 days after intervention. Method of measurement: Microgram Per Litrer(for Liver Enzyme) - Miligram Per Deciliter(for Billi). | — |
Countries
Iran (Islamic Republic of)
Contacts
Urmia Medical University