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Livergol Effect on Decrease of Hepatotoxicity caused by Chemotherapy Drugs

? The Evaluatin of Effectiveness of the Milk Testhile for Hepatoxicity in Children with Acute Lymphoblastic Leukemia(ALL)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170821035831N2
Enrollment
50
Registered
2018-02-14
Start date
2017-04-19
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute lymphoblastic leukaemia [ALL].

Interventions

Sponsors

Urmia Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Days to 15 Years

Inclusion criteria

Inclusion criteria: ALL diagnosis based on the criteria of the International Institute of Cancer with initial involvement of more than 20% of bone marrow Hepatotoxicity of Grade 2 and 3 in each of the following four cases based on the criteria of the International Institute of Cancer: Aminoalanine Transferase (ALT); Aspartate Aminotransferase (AST); Total Bilirubin (TB) ALL patients in the chemotherapy maintenance phase. ALL patients, 15-2 years old Patients ALL Pre Bcell, Early Pre Bcell

Exclusion criteria

Exclusion criteria: Unwillingness to participate in the studyl Extra bile duct obstruction, severe liver or kidney failure, gastrointestinal obstruction, malabsorption syndrome, viral hepatitis Grade 4 hepatotoxicity Sepsis-induced hepatotoxicity Intolerance to Oral Fluoride Deny the patient to study and continue taking the medication No regular and daily intake of medication Gastritis and other complications associated with taking Lourgal History of allergy due to previous use of loroge

Design outcomes

Primary

MeasureTime frame
Liver Enzyme (AST ALT Bill Total & Direct). Timepoint: Befor Intervention , 35 and 70 days after intervention. Method of measurement: Microgram Per Litrer(for Liver Enzyme) - Miligram Per Deciliter(for Billi).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Farid Ghazizade

Urmia Medical University

gazizades@yahoo.com+98 44 3223 7077

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 17, 2026