Osteoarthritis. Osteoarthritis of knee
Conditions
Interventions
Intervention 1: 33 patients in intervention group receives 500 milligram capsules containing powder extract of seven grams of fennel seeds and micro crystalline cellulose and magnesium stearate for or
Sponsors
Sari University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: Female patients aged 40 or over suffering from primary knee osteoarthritis knee osteoarthritis refering with middle or higher knee joint pain knee osteoarthritis confirmed by a rheumatologist
Exclusion criteria
Exclusion criteria: acute and uncontrolled diseases such as gastrointestinal ulcer/ uncontrolled hypertension/ heart attack and stroke within last 6 months secondary osteoarthritis including metabolic disorders such as diabetes mechanical factors such as hypermobility syndrome traumatic arthritis prior joint surgery and its fracture inflammatory arthritis, such as rheumatoid arthritis or other inflammatory arthropathies, gout and septic arthritis acute arthritis use of steroids within 14 days prior to study or injectable form 30 days before the study abuse of alcohol and drugs use of antidepressants epilepsy history of celery allergy estrogen-dependent women diseases pregnancy use of estrogen-containing drugs renal failure or hyperkalemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score. Timepoint: first day and 14th day. Method of measurement: Visual Analog Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Stiffness and physical function of the knee. Timepoint: First day and 14th day. Method of measurement: WOMAC Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyde Sedighe Yousefi
Sari University of Medical Sciences
Outcome results
None listed