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The effect of silymarin on Parkinson's disease

Evaluation of the effect of Sillymarin on motor manifestations of Parkinsonian patients : A randomized clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017081435697N1
Enrollment
40
Registered
2017-09-10
Start date
2017-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's disease. Incl.: Hemiparkinsonism Paralysis agitans or Parkinsonism

Interventions

Intervention 1: In the intervention group, the drug Livergol (silymarin) at a dose of 140 mg three times a day for three months. Intervention 2: In the control group placebo will be given in the same
Treatment - Drugs
Placebo
In the intervention group, the drug Livergol (silymarin) at a dose of 140 mg three times a day for three months.
In the control group placebo will be given in the same shape of studied drug(silymarine)

Sponsors

Vice chancellor for research, Urmia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age of at least 50 years; At least 6 months have passed since their diagnosis; Treated with anti-Parkinson drugs; Have not other neurological diseases (Alzheimer's, CVA history, etc.) Exclusion criteria: Hospitalization; Surgery; Allergy to Silymarin or drug related reactions.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Movement disorders. Timepoint: monthly. Method of measurement: Modified Hoehn and Yahr Scale.

Secondary

MeasureTime frame
Life quality. Timepoint: monthly. Method of measurement: questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hamdolah Sharifi

Urmia University of Medical Sciences

sharifi.h@umsu.ac.ir+98 44 3275 4992

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026