Using of combination of bupivacaine 1 mg and fentanyle 20 mg for spinal anesthesia in transurethral resection of prostate surgery

Evaluation of the effect of spinal anesthesia with combination of 0.5% hyperbaric bupivacaine 1 mg (0.2 mL)+fentanyl 20 µg (0.4 mL)+5% dextrose solution 1.4 mL (total 2 mL)on postoperative pain in transurethral resection of prostate surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017081221383N8

Enrollment

Registered

2017-10-17

Start date

2017-05-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intrathecal injection in transuretheral resection of prostat surgeries.

Interventions

Intervention 1: Intrathecal injection of 0.5% Hyperbaric bupivacaine 1mg (0.2 cc) + 5% Dextrose (1.4 cc)+ Fentanyl 20 µg (0.4 cc). Intervention 2: Administration of hyperbaric bupivacaine 10 mg intra

Prevention

Intrathecal injection of 0.5% Hyperbaric bupivacaine 1mg (0.2 cc) + 5% Dextrose (1.4 cc)+ Fentanyl 20 µg (0.4 cc)

Administration of hyperbaric bupivacaine 10 mg intrathecally

Eligibility

Sex/Gender

Male

Age

50 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: All the patients aged 50 to 85 years old with american society of anesthesia physical classificaton system (ASA) 1 or 2 who were scheduled for prostatic endoscopic surgery under spinal anesthesia. Exclusion criteria: Patients with histories of back surgery, infection in the back, coagulopathy, hypersensitivity to local anesthetics or opioids, mental disturbance, or neurological disease were excluded.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Postoperative pain. Timepoint: 15, 30 minutes and 2, 6, 12, 24 hours after surgery. Method of measurement: visual analog scale (VAS).;The doses of meperidine. Timepoint: Within 24 hours. Method of measurement: Based on the total dose of injections in 24 hours (questionnaire).	—

Secondary

Measure	Time frame
Motor block. Timepoint: When the peak sensory and cold blocks were obtained at dermatom of T10. Method of measurement: modified Bromage scale.;Nausea. Timepoint: During the surgery and immediately, 15 and 30 minutes, 2, 6, 12, 24 hours after surgery. Method of measurement: Visual analog scale (VAS).;Vomiting. Timepoint: During the surgery to 24 hours after surgery. Method of measurement: vomiting or not during surgery and upto 24 hours thereafter.;Mean arterial pressure. Timepoint: each 5 minute to the end of the surgery. Method of measurement: mmhg with oscillometric barometer.;Heart rate. Timepoint: each 5 minutes to the end of the surgery. Method of measurement: beat per minutes with digital ECG monitor.	—

Measure

Time frame

Motor block. Timepoint: When the peak sensory and cold blocks were obtained at dermatom of T10. Method of measurement: modified Bromage scale.;Nausea. Timepoint: During the surgery and immediately, 15 and 30 minutes, 2, 6, 12, 24 hours after surgery. Method of measurement: Visual analog scale (VAS).;Vomiting. Timepoint: During the surgery to 24 hours after surgery. Method of measurement: vomiting or not during surgery and upto 24 hours thereafter.;Mean arterial pressure. Timepoint: each 5 minute to the end of the surgery. Method of measurement: mmhg with oscillometric barometer.;Heart rate. Timepoint: each 5 minutes to the end of the surgery. Method of measurement: beat per minutes with digital ECG monitor.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Amir Sabertanha

Birjand University of Medical Sciences

amirsaber43@yahoo.comamirsaber63@gmail.com+98 56 3243 2778

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026