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The effects of aloe vera gel on pain and function among patients with knee osteoarthritis

Investigating the effects of Phonophoresis of aloe vera gel on pain and function in patients with knee osteoarthritis (grade 1-3 Kellgren-Lawrence)

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017081215932N13
Enrollment
51
Registered
2017-10-24
Start date
2017-11-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis. Arthrosis, unspecified

Interventions

Intervention 1: Patients in group A will receive 10 sessions of physical therapy at the knee area as following: Phonophrosis of Aloe vera gel combined with exercise therapy. 30 ml of 2% Aloe vera gel
Rehabilitation
Patients in group A will receive 10 sessions of physical therapy at the knee area as following: Phonophrosis of Aloe vera gel combined with exercise therapy. 30 ml of 2% Aloe vera gel is used for any
Patients in B group will receive 10 sessions of physical therapy at the knee area as following:Ultrasound with conventional gel combined with exercise therapy.Ultrasound therapy in this group is simil
Patients in C group will receive 10 sessions of physical therapy at the knee area as following: sham US therapy with Aloe vera gel combined with exercise therapy.Treatment in this group is similar to

Sponsors

Shiraz University of Medical Scienses
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1.Age from 45 to 70 years 2.Severity of knee Osteoarthritis ranging from 1 to 3 using kellgren Lawrence scale. 3.The WOMAC score should be at least 25. 4.Pain severity should be 5 or more according to numerical rating scale. 5.The target knee is the more painful knee or the knee with more symptoms. If symptoms are similar in both sides the right knee will be considered as the target. 6.All patients fulfill the American College of Rheumatology criteria for knee Osteoarthritis,including both clinical and Radiographical signs of Osteoarthritis. according to this criterion, the diagnosis of Osteoarthritis is confirmed by the presence of items 1, 2 or 1, 3, 5, 6 or 1, 4, 5, 6 from the following list: 1. Knee pain for most days of previous month 2. Osteophytes at joint margins on radiographs 3. Synovial fluid typical of osteoarthritis (laboratory) 4. Age 40 years or older 5. Crepitus on active joint motion 6. Morning stiffness lasting 30 min or less Exclusion criteria: 1.Other muscluskeletal problems associated with knee joint such as RA and other Rheumatic diseases. 2.History of trauma , accident or surgery in the study knee. 3.Other chronic or systemic disease such as diabetes ,thyroid disease. 4.patients received physiotherapy treatment for their knees in the preceding 3 month. 5.Arthroplasty in each of the Lower Extremity joints or other painful conditions. 6.wound in the target knee. 7.Skin disease. 8.Joint fluid extraction, intra articular knee injection, PRP in the last six month. 9.Frequent use of NASIDs or other analgesics

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: before treatment, the day after the last treatment session and one month after the treatment program. Method of measurement: NRS scale.;Function. Timepoint: before treatment, the day after the last treatment session and one month after the treatment program. Method of measurement: WOMAC questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSobhan Arjmand

Shiraz University of Medical Sciences

sobhanarjomand72@gmail.com+98 71 1627 1552

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026