Polycystic ovarian syndrome. Polycystic ovarian syndrome
Conditions
Interventions
Intervention 1: Intervention group: Participants will receive a personalized MIND diet using a co-design approach involving the patient, researcher, and physician and delivered via social media. Basal
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Willingness to participate in the study Diagnosis of polycystic ovary syndrome (PCOS) based on the Rotterdam criteria At least 2 weeks having passed since the diagnosis and initial treatment of PCOS Age between 18 and 45 years BMI between 25 and 35 Having a smartphone
Exclusion criteria
Exclusion criteria: Pregnancy or breastfeeding History of liver disease, renal failure, heart failure, infectious or inflammatory diseases, diabetes, or any type of cancer Following special diets or weight-loss diets during the past three months Use of corticosteroids Avoidance of any herbal medicine in any form (such as tablets, capsules, powder, syrup, or oil). This restriction includes all unauthorized herbal infusions (such as mint, borage, chamomile, lemon verbena, thyme, cinnamon, ginger, etc.) as well as herbal products with claimed therapeutic effects (such as supplements containing inositol, berberine, vitex extract, black cohosh, and similar products). Cigarette smoking
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Homeostatic Model Assessment of Insulin Resistance (HOMA-IR). Timepoint: At baseline (before the start of the intervention) and 90 days after initiating the diet. Method of measurement: Calculation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting blood sugar. Timepoint: At baseline (before the start of the intervention) and 90 days after initiating the diet. Method of measurement: Enzymatic method.;Serum insulin. Timepoint: At baseline (before the start of the intervention) and 90 days after initiating the diet. Method of measurement: Elisa method.;HOMA-ß: The homeostasis model assessment of pancreatic ß-cell function. Timepoint: At baseline (before the start of the intervention) and 90 days after initiating the diet. Method of measurement: Calculating.;QUICKI: The quantitative insulin-sensitivity check index. Timepoint: At baseline (before the start of the intervention) and 90 days after initiating the diet. Method of measurement: Calculating.;Serum total Testosterone. Timepoint: At baseline (before the start of the intervention) and 90 days after initiating the diet. Method of measurement: Elisa method.;Serum Dehydroepiandrosterone sulfate. Timepoint: At baseline (before the start of the intervention) and 90 days after initiating the diet. Method of measurement: Elisa method.;Serum triglyceride (TG). Timepoint: At baseline (before the start of the intervention) and 90 days after initiating the diet. Method of measurement: Enzymatic method.;Serum total cholesterol. Timepoint: At baseline (before the start of the intervention) and 90 days after initiating the diet. Method of measurement: Enzymatic method.;Low density lipoprotein cholestrol (LDL-C). Timepoint: At baseline (before the start of the intervention) and 90 days after initiating the diet. Method of measurement: Enzymatic method.;High density lipoprotein cholestrol (HDL-C). Timepoint: At baseline (before the start of the intervention) and 90 days after initiating the diet. Method of measurement: Enzymatic method.;C reactive protein quantitive (CRP Quantitive). Timepoint: At baseline (before the start of the intervention) and 90 days after initiating the diet. Method of measurement: Elisa method.;Weight. Timepoint: At baseline (before the star | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactsakineh shab bidar
Tehran University of Medical Sciences
Outcome results
None listed