Effect of propofol-ketamine and propofol-sufentanil on sedation and analgesia in painful diagnostic methods in children with hematological malignancies

Comparative evaluation of the effect of the two combinations of Propofol-Ketamine and Propofol-Sufentanil on sedation and analgesia during painful diagnostic procedures in children with hematologic malignancies

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170809035601N9

Enrollment

120

Registered

2018-10-23

Start date

2017-03-21

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute lymphoblastic leukaemia [ALL]. Acute lymphoblastic leukemia [ALL]

Interventions

Intervention 1: In the PK group, propofol 1mg / kg with 5mg / cc of vectamine (0 / 3mg / kg) with 5mg / cc concentration of drug was added to 20 cc and the infusion of the drug continued to reach the

Eligibility

Sex/Gender

All

Age

1 Years to 14 Years

Inclusion criteria

Inclusion criteria: Children aged 1 to 14 years Hematologic malignancies Acute lymphoblastic leukemia

Exclusion criteria

Exclusion criteria: A recent trauma to the head Cardiovascular, pulmonary, or liver diseases Epilepsy, seizure or neurological disorder Use of analgesic or sedative medications before surgery Chronic pain syndrome History of allergy to the drugs studied

Design outcomes

Primary

Measure	Time frame
Sedation level. Timepoint: During procedure. Method of measurement: university of michigan sedation scale.	—

Secondary

Measure	Time frame
Analgesia. Timepoint: During procedure. Method of measurement: Universal Pain Assessment Tool.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamidreza shetabi

Esfahan University of Medical Sciences

hamidshetabi@med.mui.ac.ir+98 31 3668 5555

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026