Acute lymphoblastic leukaemia [ALL]. Acute lymphoblastic leukemia [ALL]
Conditions
Interventions
Intervention 1: Two syringes containing the drug dosage required for each 10 kg body weight. Syringes will be prepared as propofol (7.5mg), Sufentanil 5 µg for PS group. Intervention 2: Control group
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
2 Years to 14 Years
Inclusion criteria
Inclusion criteria: Children 2 to 14 years old with Hematologic Malignancy Candidate for painful diagnostic procedures
Exclusion criteria
Exclusion criteria: History of hypersensitivity or allergic reaction to any medication regimen Use of any analgesic and anesthetic drug Cardiovascular disease, respiratory disease, liver disease, epilepsy or a history of seizures, neurological disorders, brain tumor or metastasis. The presence of chronic pain syndromes Head injuries
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation level. Timepoint: During Procedure. Method of measurement: University of Michigan Sedation Scale (UMSS).;Analgesia. Timepoint: during procedure. Method of measurement: Universal Pain Assessment Tool(UPAT). | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic changes ( Heart rate , Systolic and Diastolic blood pressure, Mean atria pressure). Timepoint: Before and during the procedure and recovery time. Method of measurement: Cardiac monitoring and automatic blood pressure monitoring.;Arterial oxygen saturation. Timepoint: Before and during the procedure and recovery time. Method of measurement: Pulse oximeter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamidreza Shetabi
Esfahan University of Medical Sciences
Outcome results
None listed