Acute lymphoblastic leukaemia [ALL]. Acute lymphoblastic leukemia [ALL]
Conditions
Interventions
Intervention 1: Intervention group: Group 1 (propofol-ketamine) 1 mg / kg propofol plus 0.3mg / kg ketamine were injected doubled. Intervention 2: Intervention group: Group 2 (ketamine-sufentanil) 1mg
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
6 Months to 14 Years
Inclusion criteria
Inclusion criteria: children between 6 month and 14 years old Candid bone marrow aspiration and lumbar Puncture
Exclusion criteria
Exclusion criteria: Hypersensitivity or allergic reaction to any medication regimen The use of analgesic and anesthetic ago Cardiovascular disease, respiratory disease, liver disease, epilepsy or a history of seizures, neurological disorders, brain tumor or metastasis. There are chronic pain syndromes. Head injuries
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation Level. Timepoint: During Procedure. Method of measurement: University of Michigan Sedation Scale (UMSS).;Analgesia. Timepoint: During Procedure. Method of measurement: Universal Pain Assessment Tool (UPAT). | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic changes ( Heart rate , Systolic and Diastolic blood pressure, Mean atria pressure). Timepoint: Before and during the procedure and recovery time. Method of measurement: Cardiac monitoring and automatic blood pressure monitoring.;Arterial oxygen saturation. Timepoint: Before and during the procedure and recovery time. Method of measurement: Pulse oximeter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamidreza Shetabi
Esfahan University of Medical Sciences
Outcome results
None listed