Skip to content

The effect of sedation of fentanyl-etomidate, fentanyl-propofol and fentanyl-midazolam in phacoamulsification

Comparison of fentanyl-etomidate, fentanyl-propofol and fentanyl-midazolam for sedation in phacoemulsification

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170809035601N10
Enrollment
150
Registered
2018-12-29
Start date
2017-11-01
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract surgery. Cataract surgery

Interventions

Intervention 1: Intervention group: patients in group (E )received 0.1 mg/kg etomidate. In case of need, 4 mg etomidate will be injected as a rescue dose. At the end of the prescribed total dose is re

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 85 Years

Inclusion criteria

Inclusion criteria: Patients who are candidates for Phacoemulsification cataract surgery Patients who are satisfied to enter the study Patients aged 35-85 years old patients with ASA class 1 and 2

Exclusion criteria

Exclusion criteria: History of any allergy or allergic reaction to any of medications used in the study History of head injury High intraocular pressure or intracranial pressure Cardiovascular risk Hypertension Severe respiratory disease Advanced liver disease Epilepsy or history of seizure Nervous system disorders The presence of any tumor or brain metastasis Use of any analgesic and anesthetic drugs Chronic pain syndroms Patients who are not satisfied to enter the study Pregnant women

Design outcomes

Primary

MeasureTime frame
Sedation level. Timepoint: After induction of anesthesia, during the procedure every 5 minutes. Method of measurement: Modified ramsay sedation scale (RSS).

Secondary

MeasureTime frame
Mean Atrial Pressure. Timepoint: Before surgery, every 5 minutes during surgery and after the surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Pressure gauge.;Oxygen saturation percentage. Timepoint: Before surgery, every 5 minutes during surgery and after the surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Pulse oximetry.;Heart rate. Timepoint: Before surgery, every 5 minutes during surgery and after the surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Pulse oximetry.;Adverse drug reaction. Timepoint: Before surgery, every 5 minutes during surgery and after the surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Adverse drug reaction questionnaire.;Recovery time. Timepoint: From the end of the surgery to the time exit Recovery. Method of measurement: Minute.;Surgeon satisfaction. Timepoint: End of surgery. Method of measurement: Likert scale.;Patient satisfaction. Timepoint: End of Recovery. Method of measurement: Likert scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactIsfahan University of Medical Sciences

Esfahan University of Medical Sciences

hamidshetabi@med.mui.ac.ir+98 31 3668 8138

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026