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Nebulized Budesonide and asthma attack

The effect of nebulized Budesonide on spirometric indexes in patients at asthma attack phase

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170808035565N4
Enrollment
47
Registered
2019-02-16
Start date
2018-03-01
Completion date
Unknown
Last updated
2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma. Asthma

Interventions

Intervention 1: Intervention group: This group received 2 mg of budesonide (Pulmicort Nebuampul 0.5 mg / ml) in a 15-minute period. Intervention 2: The control group received 4 ml of normal saline ser

Sponsors

Sari University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: History of at least 6 months of asthma No need for a ventilator Decrease FEV1, PEF and FEV1 / FVC FEV1 Increase greater than 200 cc or 12% after salbutamol administration in spirometry

Exclusion criteria

Exclusion criteria: The history of infectious diseases such as tuberculosis, recent respiratory infections, bronchiectasis and acute or chronic diarrhea Probability of malignancy based on examination Rheumatic arthritis, degenerative joint disease, vasculitis

Design outcomes

Primary

MeasureTime frame
Forced expiratory volume in 1 second (FEV1). Timepoint: Before prescribing medications, 30 minutes and one hour after administration. Method of measurement: spirometry.;Forced expiratory volume in 1 second (FEV1) / Forced vital capacity (FVC) ratio. Timepoint: Before prescribing medications, 30 minutes and one hour after administration. Method of measurement: spirometry.

Secondary

MeasureTime frame
Peak Expiratory Flow Rate. Timepoint: Before prescribing medications, 30 minutes and one hour after administration. Method of measurement: spirometry.;Severity of respiratory distress. Timepoint: Before prescribing medications, 30 minutes and one hour after administration. Method of measurement: spirometry.;Adverse effects. Timepoint: Before prescribing medications, 30 minutes and one hour after administration. Method of measurement: spirometry.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Hosein Montazer

Sari University of Medical Sciences

hmontazer@mazums.ac.ir+98 11 3336 1700

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026