Chronic obstructive pulmonary disease exacerbation. Chronic obstructive pulmonary disease with (acute) exacerbation
Conditions
Interventions
Intervention 1: Intervention group: The case group received 2 mg of budesonide (Pulmicort Nebuampul 0.5 mg / ml) in a 15-minute period. Intervention 2: Control group: The control group received 4 ml o
Sponsors
Sari University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: COPD exacerbation patients FEV1/FVC less than 70% No need for ventilator
Exclusion criteria
Exclusion criteria: FEV1 Increase greater than 200 cc or 12% after salbutamol administration in spirometry The history of infectious diseases such as tuberculosis, recent respiratory infections, bronchiectasis and acute or chronic diarrhea Probability of malignancy based on examination Rheumatic arthritis, degenerative joint disease, vasculitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Forced expiratory volume in 1 second (FEV1). Timepoint: Before prescribing medications, 30 minutes and one hour after administration. Method of measurement: spirometry.;Forced vital capacity. Timepoint: Before prescribing medications, 30 minutes and one hour after administration. Method of measurement: spirometry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Peak Expiratory Flow Rate. Timepoint: Before prescribing medications, 30 minutes and one hour after administration. Method of measurement: spirometry.;Severity of respiratory distress. Timepoint: Before prescribing medications, as well as 30 minutes and one hour after administration. Method of measurement: Accessory muscle score.;Adverse effect. Timepoint: Before prescribing medications, as well as 30 minutes and one hour after administration. Method of measurement: Patient evaluation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Hosein Montazer
Sari University of Medical Sciences
Outcome results
None listed