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Comparison of Effect Slow and Fast injection Metoclopramide on Mental Restlessness and Motionless rest cancer patients

Comparison of slow and Boluse Infusion of Metochelopramid for Akathisia of Paitients with Cancer

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170808035565N2
Enrollment
112
Registered
2018-01-12
Start date
2018-01-10
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Akathisia. Other specified extrapyramidal and movement disorders

Interventions

Intervention 1: Intervention group: Patients with a Slow Infusion of Metoclopramide 20 mg of Plasil in 20 Minutes will be prescribed. Intervention 2: Intervention group: Patients will be given Infusio
Treatment - Drugs
Intervention group: Patients with a Slow Infusion of Metoclopramide 20 mg of Plasil in 20 Minutes will be prescribed.
Intervention group: Patients will be given Infusion with Bolus Placebo 20 mg of Plasil within 2 Minutes.
Control group: Patients will be given Infusion Bolus Metoclopramide 20 mg of Plasil within 2 Minutes.
Control group: Patients will be given a Placebo Slow Infusion of 20 mg Plasil in 20 Minutes.

Sponsors

Sari University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with Cancer over 19 Years of Age will be admitted to the Emergency Department at Imam Hospital for any Reason, Indicating Metoclopramide Infusion.

Exclusion criteria

Exclusion criteria: Patients who are not able to give informed Consent Patients who have Metoclopramide before taking Metoclopramide have Actagenia Patients with Parkinson's Disease and Restless Legs Syndrome Patients with Refractory Nausea due to the Underlying problem, such as brain Hemorrhage Patients who received Dopamine Antagonists over the past 24 Hours

Design outcomes

Primary

MeasureTime frame
Akathisia. Timepoint: The primary and secondary consequences will be measured at intervals of 0, 30, 60 and 120 minutes after Metoclopramide administration. Method of measurement: The Akathisia measure will use the Henry Akathisia Rating Scale.

Secondary

MeasureTime frame
Nausea. Timepoint: The Primary and Secondary Consequences will be measured at Intervals of 0, 30, 60 and 120 minutes after Metoclopramide Administration. Method of measurement: It will be measured using the VAS scale.;Drowsiness. Timepoint: The Primary and Secondary Consequences will be measured at Intervals of 0, 30, 60 and 120 minutes after Metoclopramide Administration. Method of measurement: The Ramsay Sedation Scale will be used to Measure Drowsiness.;The Patient's Vital Signs include pulse and Blood Pressure, Allergic Reaction. Timepoint: The Primary and Secondary Consequences will be measured at Intervals of 0, 30, 60 and 120 minutes after Metoclopramide Administration. Method of measurement: Examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEnsieh Taghizadeh

Sari University of Medical Sciences

taghizadehensieh@gmail.com+98 11 3448 4859

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026