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The effect of fourteen days regimen of four medications “bismuthe subcirate, pantoprazole, amoxicilline, clarithromycin” and seven days sequential regimen of “bismuthe subcirate, pantoprazole, amoxicilline, meteronidazole” and “bismuthe subcirate, pantoprazole, amoxicilline, furazolidone” in helicobacter pylori eradication

Comparison of helicobacter pylori eradication of fourteen days regimen of four medications “bismuthe subcirate, pantoprazole, amoxicilline, clarithromycin” with seven days sequential regimen of “bismuthe subcirate, pantoprazole, amoxicilline, meteronidazole” and “bismuthe subcirate, pantoprazole, amoxicilline, furazolidone”

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201708071155N26
Enrollment
344
Registered
2017-08-08
Start date
2017-07-13
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori. Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters

Interventions

Intervention group takethe 14 days treatment of bismuthe subcirate 240 mg twice a day made by Kimidarou, pantoprazole 20 mg twice a day made by Takeda, amoxicilline 1 gr twice a day made by Kosar, cl
first 7 days of bismuthe subcirate 240 mg twice a day made by Kimidarou, pantoprazole 20 mg twice a day made by Takeda, amoxicilline 1 gr twice a day made by Kosar, meteronidazole 500 mg twice a day m
Treatment - Drugs

Sponsors

Guilan Univercity of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: • Inclusion criteria: Positive helicobacter pylori in the endoscopy and no therapeutic regimen for treatment • Exclusion criteria: Pregnant and breast feeding women, gastric and esophageal malignancy, cirrhosis, heart and kidney failure, history of seizure, hematologic diseases, and allergy to medications, patients with incomplete treatment period, severe side effects, and no satisfaction to continue treatment

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Helicobacter pylori eradication. Timepoint: 12 weeks. Method of measurement: Ureas Breath Test with C14.

Secondary

MeasureTime frame
Comparison of helicobacter pylori eradication of fourteen days regimen of four medications “bismuthe subcirate, pantoprazole, amoxicilline, clarithromycin” with seven days sequential regimen of “bismuthe subcirate, pantoprazole, amoxicilline, meteronidazole” and “bismuthe subcirate, pantoprazole, amoxicilline, furazolidone”. Timepoint: 2-4 weeks. Method of measurement: 2-4 weeks.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Farahnaz Joukar

Gastrointestinal and Liver Diseases Research Center

farajov@gmail.com+98 13 3353 5116

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026