evaluation of topical niosomal zinc sulphate in leishmaniasis

Evaluation of efficacy of topical niosomal 2 % zinc sulfate plus intralesional glucantime in comparison with cryotherapy PLUS intralesional glucantime in the treatment of acute cutaneous leishmaniasis.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170806035524N4

Enrollment

Registered

2018-05-07

Start date

2018-01-21

Completion date

Unknown

Last updated

2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute cutaneous leishmaniaisis. Cutaneous leishmaniasis

Interventions

Intervention 1: Intervention group:treatment of cutaneous leishmaniasis with weekly intralesional glucantime plus twice daily niosomal topical zinc sulphate. Intervention 2: Control group: treatment o

Eligibility

Sex/Gender

All

Age

2 Years to No maximum

Inclusion criteria

Inclusion criteria: acute cutaneous leishmaniasis(urban type) duration less than 6 months wash out period of 1 month

Exclusion criteria

Exclusion criteria: pregnancy nursing age less than 2 years old number of lesions more than 5 sensitization to zinc sulphate or glucantime lesions on face or joint lesions larger than 5 centimeter

Design outcomes

Primary

Measure	Time frame
Reduction in induration of the lesion. Timepoint: at BASE -LINE AND IN 2,4,6,8,10,12 WEEKS and 3 months after end of the treatment. Method of measurement: by measuring induration of the lesions (largest diameter) by transparent paper.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahin aflatoonian

Kerman University of Medical Sciences

maaflatoonian@gmail.com+98 34 3132 8328

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026