Effect of fluid therapy on Creatinine level in post-renal transplant patients

Clinical trials of effect of fluid therapy with half saline compared to normal saline on Creatinine level in post-renal transplant patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017080535510N1

Enrollment

100

Registered

2017-09-13

Start date

2017-07-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease. Chronic kidney disease

Interventions

Intervention 1: Control group: Serum normal saline plus 50 mili-Equivalents Sodium Bicarbonate will be infused. Intervention 2: Intervention group: Serum half Saline plus 250 mili-Equivalents Sodium B

Prevention

Control group: Serum normal saline plus 50 mili-Equivalents Sodium Bicarbonate will be infused.

Intervention group: Serum half Saline plus 250 mili-Equivalents Sodium Bicarbonate will be infused.

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age between 18 to 65 years; Exclusion criteria: The patient's potassium is higher than 5.5; Patients with chronic heart failure Ejection Fraction less than 30%; Patients with liver failure; The patient needs to have colloidal fluid and blood intake; Severe acidosis;

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Creatinine. Timepoint: In the first, second, third and seventh days after the intervention. Method of measurement: Blood test.;Urine volume. Timepoint: In the first, second, third and seventh days after the intervention. Method of measurement: Urine test.	—

Secondary

Measure	Time frame
Systolic blood pressure. Timepoint: In the first, second, third and seventh days after the intervention. Method of measurement: Invasive blood pressure monitor.;Systolic blood pressure. Timepoint: In the first, second, third and seventh days after the intervention. Method of measurement: Invasive blood pressure monitor.;Heart rate per minute. Timepoint: In the first, second, third and seventh days after the intervention. Method of measurement: Invasive blood pressure monitor.	—

Measure

Time frame

Systolic blood pressure. Timepoint: In the first, second, third and seventh days after the intervention. Method of measurement: Invasive blood pressure monitor.;Systolic blood pressure. Timepoint: In the first, second, third and seventh days after the intervention. Method of measurement: Invasive blood pressure monitor.;Heart rate per minute. Timepoint: In the first, second, third and seventh days after the intervention. Method of measurement: Invasive blood pressure monitor.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohadeseh Shafiee

Tehran University of Medical Sciences

mds.shafiei@gmail.com+98 21 4466 3963

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026